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An oxysterol; suppresses endogenous cholesterol synthesis by binding INSIG proteins and preventing SREBPs from being transported to the Golgi; inhibits IgA class switching induced by LPS and various cytokines in B cells (IC50 = ~50 nM); inhibits replication of SARS-CoV-2 in Vero cells (EC50 = 3.675 µM) and reduces increases in viral protein production in infected Vero cells when used prior to infection; reduces viral RNA loads in the lung and trachea in a mouse model of SARS-CoV-2 infection at 100 mg/kg per day; serum levels are increased in patients with SARS-CoV-2.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A triacylglycerol; been used to characterize the functionality of R. oryzae lipase for regiodistribution analysis of fats containing medium- and short-chain fatty acids
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Empirical Formula (Hill Notation): C48H96NO8P, Molecular Weight: 846.25, Purity >99%. Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
DSPE-PEG2000-cRGD is a polyethylene glycol-lipid conjugate that links DSPE to a PEG2000 spacer terminated with a cyclic RGD peptide targeting αvβ3 integrins. Supplied as a white to off-white solid for research use, it is intended for incorporation into lipid nanoparticles and other targeted delivery systems to enhance tumor and neovasculature binding.
Provides αvβ3-targeting through a cRGD ligand.
Facilitates surface functionalization of lipid nanoparticles.
PEG2000 spacer improves circulation and steric stability.
Supplied as a solid with reported purity of ~96.2%.
Stable under frozen storage; follow supplier storage instructions.
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Lathosterol is a precursor in the cholesterol synthesis pathway. Lathosterol can be used as a biomarker of excess cholesterol production as lathosterol levels in serum corresponds with cholesterol synthesis.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
A triacylglycerol; been used to characterize the functionality of R. oryzae lipase for regiodistribution analysis of fats containing medium- and short-chain fatty acids
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More